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When it comes to managing hypertension and reducing adverse cardiovascular events, what is the ideal blood pressure figure clinicians should target? OPTICS pharmacist Henry So joins Chris for some back and forth around this question. They look at the evolution (and proliferation) of blood pressure guidelines, examine controversies around certain studies, share some of their own personal experiences with hypertension, and ultimately whether they think a lower number is necessarily better.
Before that, Chris shares some quick drug approval and guideline updates, and afterwards, we end things with a look at back at how the death of a US President 80 years ago sounded the alarm on the dangers of untreated hypertension.
Links to Material Discussed in the Episode-
Into the Clinic:
FDA Approves First New Class of Oral Antibiotics for Uncomplicated UTIs in Nearly 30 Years
High Price of GLP-1 Agents Tip Cost-Benefit Scale Unfavorably
FDA issues limited acne product recalls, AAD releases statement on benzoyl peroxide
Main Discussion:
Evidence for the Universal Blood Pressure Goal of <130/80 mm Hg Is Strong
A Randomized Trial of Intensive versus Standard Blood-Pressure Control
SPRINT: More Controversy And Confusion About ‘Landmark’ Trial
2020 International Society of Hypertension Global Hypertension Practice Guidelines
Global and European landscape of major hypertension guidelines
Blood Pressure Targets in Adults With Hypertension: A Clinical Practice Guideline From the AAFP
Hyperkalemia and Acute Kidney Injury with Spironolactone Use Among Patients with Heart Failure
Trivia Capsule:
Harold on History | Historical Perspectives on Hypertension